Venous thromboembolism (VTE), also known as blood clots, is an underdiagnosed and serious, but preventable medical condition. It is important to know about VTE because it can happen to anyone at any age and cause serious illness, disability, and in some cases, death. Given these serious complications, one might naturally expect that VTE would affect a person’s day-to-day activities and ability to work. However, the long-term impact of VTE on limiting a person’s activity or causing disability has not been well studied. This study is the first of its kind to document a relationship between VTE and subsequent work-related disability.